Browsing by Advisor/Supervisor
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Evaluation of the efficacy of selected anticancer compounds in multidrug resistant cell culture models
(North-West University (South-Africa). Potchefstroom Campus, 2019)Small cell lung cancer (SCLC) has an aggressive disseminating nature and the relapse of cancer patients after initial treatment is common. Acquired multidrug resistance (MDR) can often be attributed to over-expression of ... -
In vitro evaluation of the efficacy of selected medicinal plant extracts against multidrug resistant cancer cells
(North-West University (South-Africa). Potchefstroom Campus, 2019)Cancer is ranked as one of the leading causes of death globally, and a significant number of these diagnosed malignancies are found in lung tissue. Small cell lung cancer (SCLC) is a high grade neuroendocrine cancer, which ... -
Physico-chemical properties and intestinal epithelial permeation of baclofen solid-state forms
(North-West University (South-Africa). Potchefstroom Campus, 2019)Baclofen is a centrally acting muscle relaxant that acts as an agonist of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA). It is primarily used to treat muscle spasticity in patients with multiple sclerosis ...
