Browsing by Subject "Baclofen"
Now showing items 1-2 of 2
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The influence of buffer composition on the solubility of baclofen and sulfadoxine
(North-West University (South-Africa), 2022)The drug discovery process has developed immensely during the last couple of decades. The Biopharmaceutical Classification System (BCS) is a drug development tool that is based on correlation of solubility and membrane ... -
Physico-chemical properties and intestinal epithelial permeation of baclofen solid-state forms
(North-West University (South-Africa). Potchefstroom Campus, 2019)Baclofen is a centrally acting muscle relaxant that acts as an agonist of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA). It is primarily used to treat muscle spasticity in patients with multiple sclerosis ...