Browsing by Subject "Beads"
Now showing items 1-8 of 8
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Cassava starch as modified release excipient in selected gliclazide oral dosage forms
(North-West University (South Africa) , Potchefstroom Campus, 2015)Solid oral dosage forms are still the most leading delivery system employed commercially due to the ease in which it can be handled, administered and even transported. Several varieties of solid oral dosage forms are ... -
Chitosan beads as a delivery vehicle for the antituberculosis drug pyrazinamide
(North-West University, 2006)Controlled release systems aim at achieving a predictable and reproducible drug release profile over a desired time period. These controlled release formulations offer many advantages over conventional dosage forms. These ... -
A comparison on the release modifying behaviour of chitosan and kollidon SR
(North-West University, 2007)Controlled release formulations deliver an active ingredient over an extended period of time. It is an ideal dosage form for an active ingredient with a short elimination half-life. An active ingredient with a short ... -
Development of a mini-tablet-in-capsule dosage form for macromolecular drug delivery
(North-West University (South-Africa), 2020)Oral delivery of protein and peptide drugs faces immense challenges, partially due to the inherent unfavourable characteristics of the molecules and partially due to the unfavourable gastrointestinal environment. These ... -
Development of multiple-unit pellet systems by employing the SeDeM expert diagram system
(North-West University (South Africa), 2018)Conventional tablets and capsules are considered the most common and acceptable drug delivery systems, however, in recent years multiple unit pellet systems (MUPS) have become more popular and are considered to be an ... -
Effect of powder particle and punch type on the physical and compaction properties of tablets
(North-West University (South Africa) , Potchefstroom Campus, 2015)The main purpose of developing a dosage form or improving on a current dosage form is to ensure that the active ingredient present in the dosage form reaches the site of pharmacologic action. A dosage form must ensure ... -
Improvement of the pharmaceutical availability and membrane permeability of furosemide by formulation design
(North-West University (South-Africa), 2021)Furosemide is a well-known loop diuretic having weak acidic chemical properties. Furosemide belongs to the Biopharmaceutical Classification System (BCS) class IV because it has poor aqueous solubility and poor membrane ... -
Influence of modified release excipients on ketoprofen release from chitosan particles
(North-West University, 2005)Controlled release formulations offer many advantages over conventional dosage forms. These include reduced plasma fluctuations and improved patient comp1i:nce. Complex controlled release formulations such as those with ...