Browsing by Subject "DNA repair capacity"

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DNA damage and repair capacity in hairdressers exposed to chemical products: a pilot study

Eloff, F.C.; Preston, R.; Pretorius, P.J.; Du Plessis, J.L.; Laubscher, P.J.; Van Aarde, M.N.; Van der Westhuizen, F.H.; Franken, A. (SASOM, 2013)

Hairdressers are exposed to numerous hazardous chemical substances, some of which are known or suspected allergens, carcinogens or organic solvents. The objectives of this study were to compare DNA damage and DNA repair ...
Establishing the comet assay to determine the effects of different perturbations on DNA repair capacity

Steenkamp, Anzaan (North-West University, 2011)

Single cell gel electrophoresis (SCGE), more commonly known as the Comet assay, is an uncomplicated, affordable and versatile method for investigating DNA damage and repair. Existing comet–assay based methods were modified ...
A study of the early DNA methylation events in oxidative stressed cultured mammalian cells

Lewies, Angélique (North-West University, 2012)

Cells are continuously exposed to reactive oxygen species (ROS) causing oxidative stress. Cells can withstand and counteract ROS using defence mechanisms which range from free radical scavengers, antioxidant enzymes and ...