Browsing by Subject "Dapsone"
Now showing items 1-4 of 4
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Development and evaluation of an oral fixed–dose triple combination dosage form for artesunate, dapsone and proguanil
(North-West University, 2011)Malaria is a life–threatening disease caused by Plasmodium spp and causes over one million deaths annually. The complex life cycle of the malaria parasite offers several points of attack for the antimalarial drugs. The ... -
The development of paracetamol and dapsone amorphous solid dispersions
(North-West University (South-Africa), 2021)The development of APIs was focused on the crystalline form over the years, but as the poor solubility of new drugs increased, the focus turned to developing the amorphous form of the drug. Dapsone (DAP) is no exception, ... -
Effect of the transport medium composition on in vitro drug permeation across excised pig intestinal tissue
(North-West University (South Africa) , Potchefstroom Campus, 2016)A crucial step in the process of drug research and development is the investigation of permeation characteristics of new chemical entities across biological membranes to give an indication of their pharmacokinetic properties. ... -
Formulation, characterisation and in vivo efficacy of dapsone and proguanil in trimethylated chitosan microparticles
(2014)Malaria is an infectious disease caused by various forms of the Plasmodium parasite. It is responsible for thousands of deaths yearly with 90 % of those deaths being in sub-Saharan Africa, thus making it a disease of global ...
