Browsing by Subject "Deer mouse model"

Now showing items 1-3 of 3

Large nest building and high marble-burying: two compulsive-like phenotypes expressed by deer mice (Peromyscus maniculatus bairdii) and their unique response to serotoninergic and dopamine modulating intervention

De Brouwer, Geoffrey; Fick, Arina; Lombaard, Ané; Harvey, Brian Herbert; Wolmarans, De Wet (Elsevier, 2020)

This study aimed to further dissect the deer mouse (Peromyscus maniculatus bairdii) model of compulsive-like behavior with respect to two persistent-like behavioral phenotypes viz. large nest building (LNB) and high ...
Naturalistic operant responses in deer mice (Peromyscus maniculatus bairdii) and its response to outcome manipulation and serotonergic intervention

De Brouwer, Geoffrey; Harvey, Brian Herbert; Wolmarans, De Wet (Wolters Kluwer, 2020)

Investigating the motivational triggers underlying naturalistic compulsive-like behavior is generally regarded as challenging. To this extent, the current study aimed to establish a proof-of-concept for future investigation ...
Nest building and marble burying: Dopaminergic phenotyping of the deer mouse model of obsessive-compulsive disorder (OCD)

Lombaard, Ane (North-West University (South-Africa), 2020)

Obsessive-compulsive disorder (OCD1) is a chronic, debilitating psychiatric condition that affects 3% of the global population and is characterized by obsessions, and compulsions. 40 – 60% of patients remain treatment-resistant ...