Browsing by Subject "Drug delivery"
Now showing items 1-5 of 5
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The development and evaluation of a novel hybrid PLGA nanoparticle-Pheroid® with the potential to improve tuberculosis therapy
(North-West University, Potchefstroom Campus, 2018)The development of drug delivery technologies has the potential to bring both therapeutic and commercial value to future healthcare products. Drug delivery technologies are transport vehicles that help overcome the ... -
The effect of Pheroid® technology on the bioavailability of artemisone in primates
(2014)Malaria is one the world’s most devastating diseases. Several classes of drugs are used to treat malaria. Artemisinin combination therapy is the first line treatment of uncomplicated malaria. The artemisinin derivative, ... -
Evaluation of the oral delivery of goserelin with Pheroid® technology
(North-West University (South-Africa), 2019)The therapeutic amphiphilic peptide, goserelin, being investigated in these studies, is a type of hormone therapy generally used in addition to standard adjuvant therapy. Goserelin serves as treatment for numerous ... -
Radio-labelling as a tool to investigate the absorption and bio-distribution of selected antimalarial drugs
(2014)Previous studies have shown that the formulation of an active pharmaceutical ingredient (API) entrapped in the Pheroid® (Pheroid for simplification) delivery system enhances absorption of the API, suppresses its metabolism, ... -
Samarium oxide as a radiotracer to evaluate the in vivo biodistribution of PLGA nanoparticles
(Springer, 2015)Developing nanoparticulate delivery systems that will allow easy movement and localization of a drug to the target tissue and provide more controlled release of the drug in vivo is a challenge in nanomedicine. The aim of ...
