Browsing by Subject "NMDAR"

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S-nitrosylation and attenuation of excessive calcium flux by pentacycloundecane derivatives

Lemmer, Hendrik J.R.; Joubert, Jacques; Van Dyk, Sandra; Van der Westhuizen, Francois H.; Malan, Sarel F. (Bentham Science, 2012)

A novel series of polycyclic amines, containing nitrogen monoxide donating moieties, were synthesised and tested for calcium channel and N-methyl-D-aspartate receptor modulating activity. The synthesised compounds were ...
Synthesis, evaluation and application of polycyclic fluorescent analogues as N-methyl-D-aspartate receptor and voltage gated calcium channel ligands

Joubert, Jacques; Van Dyk, Sandra; Malan, Sarel F.; Green, Ivan R. (Elsevier, 2011)

A series of polycyclic fluorescent ligands were synthesised and evaluated in murine striatal synaptoneurosomes for N-methyl-D-aspartate receptor (NMDAR) mediated calcium flux inhibition and inhibition of calcium influx ...