Browsing by Subject "NODAGA"

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Comparison of DOTA and NODAGA as chelates for 68Ga-labelled CDP1 as novel infection PET imaging agents

Mdlophane, A.H.; Zeevaart, J.R.; Ebenhan, T.; Marjanovic-Painter, B.; Govender, T. (Springer, 2019)

The cathelicidin-derived peptide (CDP1) is a human antimicrobial peptide that preferentially targets bacterial membranes in response to infection. CDP1 was functionalised with NODAGA and DOTA for complexation with gallium-68 ...
Synthesis, in vitro evaluation, and 68Ga-radiolabeling of CDP1 toward PET/CT imaging of bacterial infection

Dutta, Jyotibon; Marjanovic-Painter, Biljana; Zeevaart, Jan Rijn; Baijnath, Sooraj; Somboro, Anou M. (Wiley, 2017)

Bacterial infections are a major concern in the human health sector due to poor diagnosis and development of multidrug-resistant strains. PET/CT provides a means for the non-invasive detection and localization of the ...