Browsing by Subject "Neurotoxicity"
Now showing items 1-4 of 4
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Effects of early-life administration of methamphetamine on the depressive-like behaviour later in life in stress-sensitive and control rats
(2013)Methamphetamine (MA) is a well-known, easily accessible and powerful psychostimulant, and its abuse has become a global problem. MA abuse affects millions of people worldwide and places an enormous burden on public healthcare ... -
Formulation, characterization and cellular toxicity of lipid based drug delivery systems for mefloquin
(North-West University, 2011)Malaria affects millions of people annually especially in third world countries. Increase in resistance and limited research being conducted adds to the global burden of malaria. Mefloquine, known for unwanted adverse ... -
The synthesis and evaluation of 1-methyl-3-pyrrolines and 1-methylpyrroles as substrates and inhibitors of monoamine oxidase B
(North-West University, 2007)Very little is known about why and how the Parkinson's disease (PD) neurodegenerative process begins and progresses. In the course of developments for treatment of PD, the discovery of the inhibition of monoamine oxidase ... -
Synthesis and in vitro antimalarial activity of esters with truncated artemisinin scaffold
(North-West University (South Africa) , Potchefstroom Campus, 2017)Malaria is an infectious disease caused by Plasmodium parasites, with P. falciparum, responsible for most cases of morbidity and mortality. In 2014, malaria killed 438 000 people, with most deaths occurring in sub-Saharan ...
