Browsing by Subject "Orbivirus"
Now showing items 1-8 of 8
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Current and next-generation bluetongue vaccines: requirements, strategies, and prospects for different field situations
(Taylor & Francis, 2017)Bluetongue virus (BTV) causes the hemorrhagic disease bluetongue (BT) in ruminants. The best way to control outbreaks is vaccination. Currently, conventionally modified-live and inactivated vaccines are commercially ... -
Development of real-time RT-PCR assays for detection and typing of epizootic haemorrhagic disease virus
(Wiley, 2017)Epizootic haemorrhagic disease virus (EHDV) is an emerging arboviral pathogen of wild and domestic ruminants worldwide. It is closely related to bluetongue virus (BTV) and is transmitted by adult females of competent ... -
Establishment of different plasmid only-based reverse genetics systems for the recovery of African horse sickness virus
(Elsevier, 2016)In an effort to simplify and expand the utility of African horse sickness virus (AHSV) reverse genetics, different plasmid-based reverse genetics systems were developed. Plasmids containing cDNAs corresponding to each of ... -
European bluetongue serotype 8: disease threat assessment for U.S. sheep
(Mary Ann Liebert Inc, 2016)Bluetongue virus (BTV) is an orbivirus transmitted by biting midges (Culicoides spp.) that can result in moderate to high morbidity and mortality primarily in sheep and white-tailed deer. Although only 5 serotypes of BTV ... -
Protective immunity of plant-produced African horse sickness virus serotype 5 chimaeric virus-like particles (VLPs) and viral protein 2 (VP2) vaccines in IFNAR -/- mice
(Elsevier, 2022)Next generation vaccines have the capability to contribute to and revolutionise the veterinary vaccine industry. African horse sickness (AHS) is caused by an arbovirus infection and is characterised by respiratory distress ... -
Requirements and comparative analysis of reverse genetics for bluetongue virus (BTV) and African horse sickness virus (AHSV)
(BioMed Central, 2016)Background Bluetongue virus (BTV) and African horse sickness virus (AHSV) are distinct arthropod borne virus species in the genus Orbivirus (Reoviridae family), causing the notifiable diseases Bluetongue and African horse ... -
A review of knowledge gaps and tools for orbivirus research
(Mary Ann Liebert, Inc, 2015)Although recognized as causing emerging and re-emerging disease outbreaks worldwide since the late 1800s, there has been growing interest in the United States and Europe in recent years in orbiviruses, their insect vectors, ... -
Virus‐induced autophagic degradation of STAT2 as a mechanism for interferon signaling blockade
(EMBO Press, 2019)The mammalian interferon (IFN) signaling pathway is a primary component of the innate antiviral response, and viral pathogens have evolved multiple mechanisms to antagonize this pathway and to facilitate infection. Bluetongue ...
