Browsing by Subject "oxidative stress"
Now showing items 1-8 of 8
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Effects of chronic methamphetamine exposure during early or late phase development in normal and social isolation reared rats
(North-West University, 2012)Methamphetamine (MA) abuse is a fast growing drug problem, and is the second most widely abused drug world-wide. MA abuse has been linked to the development of symptoms indistinguishable from schizophrenia, referred to as ... -
Evaluation of efavirenz on neurochemical and oxidative stress markers and addictive-like behaviours in rats
(North-West University, 2018)HIV positive patients treated with the antiretroviral (ARV) drug efavirenz have been observed to experience various neuropsychiatric symptoms including insomnia, dizziness, somnolence, vivid and abnormal dreams and thoughts ... -
Exploring the link between oxidative stress and the vasculature in a bi-ethnic population
(North-West University, 2019)Oxidative stress has been implicated in the development of hypertension, arterial stiffness and atherosclerosis. Optimal functioning of the enzymatic antioxidant system is central to prevent increased oxidative stress and ... -
The involvement of metallothioneins in mitochondrial function and disease
(Bentham Science, 2010)Mitochondrial oxidative phosphorylation deficiency is accompanied by various down-stream, adaptive responses which play a key role in the varied phenotypes observed when mitochondrial dysfunction occurs. These responses ... -
Ozone exposure of Flinders Sensitive Line rats is a rodent translational model of neurobiological oxidative stress with relevance for depression and antidepressant response
(Springer, 2015)Rationale Major depression has been associated with higher levels of air pollution that in turn leads to neurodegeneration via increased oxidative stress. There is a need for suitable translational animal models to study ... -
The potential benefits of red beetroot supplementation in health and disease
(MDPI, 2015)In recent years there has been a growing interest in the biological activity of red beetroot (Beta vulgaris rubra) and its potential utility as a health promoting and disease preventing functional food. As a source of ... -
The role of cherries in exercise and health
(Wiley, 2014)Recently, cherries and cherry products have received growing attention within the literature with regard to their application in both exercise and clinical paradigms. Reported to be high in anti-inflammatory and anti-oxidative ... -
Studies on Garcinia mangostana Linn as a therapeutic intervention in an immune-inflammatory model of schizophrenia
(North-West University, 2018)Schizophrenia is a life-long psychiatric disorder affecting 0.5-1% of the global population. This illness typically presents with severely debilitating clinical features in late adolescence, including positive, negative ...
