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Now showing items 1-20 of 35682
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1,3,4-Oxadiazol-2-ylbenzenesulfonamides as privileged structures for the inhibition of monoamine oxidase B
(Elsevier, 2019)The present study investigates the monoamine oxidase (MAO) inhibition properties of a series of ten 5-aryl-1,3,4-oxadiazol-2-ylbenzenesulfonamides. The target compounds were synthesized by dehydration of the corresponding ... -
1,3,7-Triethyl-substituted xanthines-possess nanomolar affinity for the adenosine A1 receptor
(Elsevier, 2015)Adenosine A1 receptors are attracting great interest as drug targets for their role in cognitive deficits. Antagonism of the adenosine A1 receptor may offer therapeutic benefits in complex neurological diseases, such as ... -
1-Bromo-2-(10 β-dihydroartemisinoxy)-ethane
(IUCr, 2010)The title compound, C17H27BrO5, DEB, is a derivative of artemisinin which is used in malaria therapy. The OR-group at C12 is cis to the CH3-group at C11 and axially oriented on ring D which has a chair conformation. The ... -
A 10-year follow-up study of demographic and cardiometabolic factors in HIV-infected South Africans
(Clinics Cardive Publishing, 2019)Objectives: Understanding of the interplay between human immunodeficiency virus (HIV) and cardiovascular disease, especially in Africa, is limited to evidence from longitudinal studies. Therefore the demographic profile ... -
100 Years of atmospheric and marine observations at the Finnish Utö Island in the Baltic Sea
(EGU, 2018)The Utö Atmospheric and Marine Research Station introduced in this paper is located on Utö Island (59°46.84′N, 21°22.13′E) at the outer edge of the Archipelago Sea, by the Baltic Sea towards the Baltic Proper. Meteorological ... -
11-Azaartemisinin cocrystals with preserved lactam : acid heterosynthons
(RSC, 2018)11-Azaartemisinin (11-Aza) is a potent anti-malarial drug more readily able to form cocrystals than its parent compound. 13 new 1 : 1 and 2 : 1 cocrystal phases from 25 mono- and bi-functional acids are reported here in ... -
13 May 1915: Bloemfontein’s night of broken glass
(School for Basic Sciences, Vaal Triangle Campus, North-West University, 2016)Less than a year after the outbreak of the Great (First World) War, the sinking of the passenger ship, RMS Lusitania on 7 May 1915 by a German submarine off the coast of Ireland and the death of 1 198 of its passengers and ... -
13CH3OH masers associated with a transient phenomenon in a high-mass young stellar object
(IOP, 2020)We report the first detection of isotopic methanol (13CH3OH) maser emission in interstellar space. The emission was detected toward the high-mass young stellar object G358.93-0.03 during monitoring of a flare in the 6.7 ... -
16SrRNA-based bacterial community profiling of Haemonchus contortus infecting Dohne Merino sheep using next generation sequencing
(North-West University (South Africa), 2019)Gastrointestinal parasitism causes major economic losses in most livestock species including small ruminants’ production throughout the world. The control of gastrointestinal nematode (GIN) parasites is mostly based on ... -
The 1960s - long hair, flowers and morality mash: Ethical appraisal of the clash that helped shape today's Western society
(Gereformeerde Teologiese Vereniging, 2009)The 1960s will be remembered as a major clash that helped shape today's Western society. Young people were breaking out of the moulds that had been cast by their parents' post-war era. The conflict brought about significant ... -
The 1973 Durban strikes: of local and international significance.
(Departement van Geskiedenis Randse Afrikaanse Universiteit / Department of History Rand Afrikaans University, 1992)• Opsomming: Die 1973 vloedgolf van stakings in Durban was vir die meeste mense 'n totaal onverwagte gebeurtenis. Met meer as 60 000 swart werkers daarby betrokke het die gebeure groot besorgdheid by privaat maatskappye, ... -
1984. Suid-Afrikaanse tydskrif vir kultuurgeskiedenis 1& 2. [Boek resensie]
(Afdeling vir Navorsing oor Streek- en Sosio-ekonomiese Geskiedenis van die lnstituut vir Geskiedenisnavorsing, RGN / Division for Research into Regional and Socio-economic History, Institute for Historical Research, HSRC, 1985) -
The 1990 Biennial National Conference for the South African society for history teaching.
(The South African Society of History Teaching, 1990) -
1994: new academic profession for a new South Africa?
(Taylor and Francis, 2015)Since 1994, the eyes of the world have been on South Africa, observing with interest the societal reconstruction project, upon which the country had embarked. In this project, higher education is both the terrain and the ... -
1D and 3D numerical simulation of the reactor cavity cooling system of a very high temperture reactor
(IHTC, 2014)To avoid accidents due to human error or the failure of components, the reactor cavity cooling system (RCCS) of a high temperature reactor must be able to operate naturally or passively safe. The RCCS can be a buoyancy ... -
1D and 3D simulation of a water cooled reactor cavity cooling system experimental facility
(North-West University (South Africa)., 2021)The fourth-generation nuclear reactors have many safety features, including the reactor cavity cooling system (RCCS). This system is intended to remove decay heat from the reactor cavity. Designs exist for both air-cooled ... -
1H NMR spectral identification of medication in cerebrospinal fluid of pediatric meningitis
(Elsevier, 2017)Exploratory metabolomics studies of cerebrospinal fluid (CSF), using proton nuclear magnetic resonance (1H NMR) spectroscopy, hold major potential application in neurodiagnostics. Such studies, however, rely upon established ... -
The 1H-NMR-based metabolite profile of acute alcohol consumption: a metabolomics intervention study
(PLoS, 2018)Metabolomics studies of disease conditions related to chronic alcohol consumption provide compelling evidence of several perturbed metabolic pathways underlying the pathophysiology of alcoholism. The objective of the present ... -
2, 10-dimethylacridin-9(10H)-one as New Synthesized Corrosion Inhibitor for C38 Steel in 0.5 M H2SO4
(ESG, 2015)The corrosion inhibition of C38 steel in 0.5 M H2SO4 solution by 2,10-dimethylacridin-9(10H)-one (DMA) has been studied using electrochemical polarization , electrochemical impedance spectroscopy (EIS) and weight loss ... -
2,4-Diamino-5-(phenylthio)-5H-chromeno [2,3-b] pyridine-3-carbonitriles as green and effective corrosion inhibitors: gravimetric, electrochemical, surface morphology and theoretical studies
(Royal Society of Chemistry, 2016)The inhibition of mild steel corrosion in 1 M HCl by three newly synthesized 2,4-diamino-5-(phenylthio)-5H-chromeno[2,3-b]pyridine-3-carbonitriles (DHPCs) namely, 2,4-diamino-7-nitro-5-(phenylthio)-5H-chromeno[2,3-b]pyri ...
