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Leptin relates to prolonged cardiovascular recovery after acute stress in Africans: the SABPA study
(Elsevier, 2016)
Background and aims
Heightened cardiovascular reactivity and delayed recovery to stress are associated with an increased risk of cardiovascular disease. Africans, who are more prone to develop hypertension, show greater ...
Nitric oxide synthesis capacity, ambulatory blood pressure and end organ damage in a black and white population: the SABPA study
(Springer, 2016)
Nitric oxide (NO) synthesis capacity is determined by the availability of substrate(s) such as l-arginine and the influence of nitric oxide synthase (NOS) inhibitors, asymmetric dimethylarginine (ADMA) and symmetric ...
The South African salt story: where are we and where are we heading?
(Karger, 2017)
Background and objectives:
The mortality and morbidity
burden caused by hypertension are preventable and therefore, efforts need to be taken to address this burden. Excess dietary sodium ...
Alcohol intake, hypertension development and mortality in black South Africans
(Sage Publishing, 2016)
Background: Excessive alcohol intake is a risk factor for cardiovascular disease (CVD) and predicts cardiovascular and
all-cause mortality. We determined which alcohol marker (self-reported alcohol intake, gamma-glutamy ...
The protective role of oestradiol against silent myocardial ischemia and hypertension risk in South African men: the SABPA study
(Elsevier, 2017)
Background
Oestradiol has a protective effect on coronary artery health in women but the effect it has on men, is controversial. A translational approach was followed to assess whether sex hormone levels are associated ...
Sodium and potassium intake in South Africa: an evaluation of 24-hour urine collections in a white, black, and Indian population
(Elsevier, 2016)
Limited number of studies on salt intake has been conducted in the South Africa. The present study established the sodium and potassium excretion (24-hour urine collection) of three different South African populations. In ...
Change in renin, cardiovascular and inflammatory markers over three years in a black and white population: the SABPA study
(BioMed Central, 2017)
Background: To investigate if percentage change (%Δ) in renin over a 3 year follow-up is associated with %Δ in
cardiovascular and inflammatory markers in a low renin bi-ethnic group.
Methods: Blood pressure, active renin, ...
The contribution of the C-824T tyrosine hydroxylase polymorphism to the prevalence of hypertension in a South African cohort: the SABPA study
(Taylor & Francis, 2013)
The C-824T single nucleotide polymorphism in the promoter region of the tyrosine hydroxylase gene has been associated with hypertension. It is well documented that African South Africans exhibit a higher prevalence of ...
Depression symptoms facilitated fibrinolytic dysregulation and future coronary artery disease risk in a black male cohort: the sympathetic activity and ambulatory blood pressure in Africans study
(Wolters Kluwer, 2017)
Background: Hypercoagulation is associated with coronary artery disease (CAD). Whether depression symptoms dysregulate inflammatory and hemostatic markers in an African cohort is not known; therefore, we assessed the ...
Longitudinal changes of cardiac troponin and inflammation reflect progressive myocyte stretch and likelihood for hypertension in a Black male cohort: the SABPA study
(Springer, 2019)
Inflammation was cross-sectionally associated with subclinical wall remodeling and hypertension. Whether longitudinal changes (∆) in inflammation, myocyte injury (troponin T), and stretch (N-terminal-pro-B-type natriuretic ...