Browsing Electronic Theses and Dissertations (ETDs) by Author "Calitz, Carlemi"
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Establishing three-dimensional cell culture models to measure biotransformation and toxicity
Calitz, Carlemi (North-West University, Potchefstroom Campus, 2018)A great proportion of new chemical entities will be terminated from the clinical drug development pipeline as a result of deficiencies in drug absorption, distribution, biotransformation and elimination as well as potential ... -
Impact of selected herbal products on intestinal epithelial permeation and metabolism of indinavir
Calitz, Carlemi (2014)Patients on anti-retroviral (ARV) drug treatment are sometimes simultaneously taking other prescribed drugs and/or over-the-counter drugs and/or herbal remedies. Pharmacokinetic drug-drug or herb-drug interactions can occur ...